Successful percutaneous treatment of complex heart disease in a stage IV non-small cell lung cancer survivor

• Published in: Giornale italiano di cardiologia (2006) Vol. 25; no. 10; p. 747
• Main Authors: Bosi, Davide, Demola, Pierluigi, Alberti, Giulia, Musto D'Amore, Sergio, Larocca, Mario, Guiducci, Vincenzo, Pinto, Carmine, Navazio, Alessandro, Tarantini, Luigi
• Format: Journal Article
• Language: Italian
• Published: Italy 01-10-2024
• Subjects: Adenocarcinoma - therapy; Angioplasty, Balloon, Coronary - methods; Aortic Valve Stenosis - surgery; Cancer Survivors; Carcinoma, Non-Small-Cell Lung - therapy; Coronary Stenosis - therapy; Drug-Eluting Stents; Heart Valve Prosthesis Implantation - methods; Humans; Kidney Neoplasms - pathology; Kidney Neoplasms - therapy; Lung Neoplasms - pathology; Lung Neoplasms - secondary; Lung Neoplasms - therapy; Male; Middle Aged; Neoplasm Staging; Treatment Outcome
• ISSN: 1972-6481
• DOI: 10.1714/4336.43217

The presence of metastatic cancer represents a high-risk condition for the treatment of heart disease requiring surgical or percutaneous procedures. We present the case of a 58-year-old man with pulmonary adenocarcinoma and renal metastases surviving more than 3 years after chemotherapy and immunotherapy suffering dyspnea and chest pain on minimal exertion due to 99% anterior coronary artery stenosis associated with severe aortic stenosis of a bicuspid valve. We treated the cardiac lesions in two steps by coronary angioplasty with drug-eluting stent implantation followed by percutaneous prosthetic aortic valve replacement. The procedures were successful with resolution of the symptoms and recovery of the usual ECOG-PS 0-1 functional capacity which persists 24 months after cardiac procedures. This case demonstrates that the multidisciplinary collaboration between oncologists and cardiologists with a personalized patient-centered approach allows to treat complex clinical situations successfully in the emerging category of patients surviving with metastatic cancer.