Clinical application of phage immunoprecipitation sequencing to diagnose enterovirus D68 as the underlying etiology in a case of Gullain-Barré syndrome

Gullain-Barré syndrome (GBS) is an acute peripheral neuropathy often preceded by respiratory or gastrointestinal infections, though molecular testing of cerebrospinal fluid (CSF) is often inconclusive. In a recent case of severe pediatric GBS in British Columbia, Canada, we detected CSF antibodies a...

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Bibliographic Details
Published in:	The Journal of infectious diseases
Main Authors:	Li, Fang Fang, Faber, Alison, Caleta, Jessica M, Goldfarb, David M, Sekirov, Inna, Prystajecky, Natalie A, Srigley, Jocelyn A, Mishaal, Ram, Jassem, Agatha N
Format:	Journal Article
Language:	English
Published:	United States 31-08-2024
Subjects:	Enterovirus D68 Phage immunoprecipitation sequencing Guillain-Barré syndrome
Online Access:	Get full text
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Summary:	Gullain-Barré syndrome (GBS) is an acute peripheral neuropathy often preceded by respiratory or gastrointestinal infections, though molecular testing of cerebrospinal fluid (CSF) is often inconclusive. In a recent case of severe pediatric GBS in British Columbia, Canada, we detected CSF antibodies against enterovirus D (EV-D) to link GBS with prior EV-D68 respiratory infection.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1537-6613 1537-6613
DOI:	10.1093/infdis/jiae411