The endoscopic transnasal approach in management of the sinonasal tumor invading the anterior skull base

• Published in: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Vol. 56; no. 1; p. 11
• Main Authors: Liu, Q, Wang, H, Sun, X C, Yu, H P, Gu, Y R, Li, H Y, Zhao, W D, Yu, H M, Wang, D H
• Format: Journal Article
• Language: Chinese
• Published: China 07-01-2021
• Subjects: Female; Humans; Male; Middle Aged; Nasal Cavity; Neoplasm Recurrence, Local; Nose Neoplasms - surgery; Retrospective Studies; Skull Base - surgery; Skull Base Neoplasms - surgery
• ISSN: 1673-0860
• DOI: 10.3760/cma.j.cn115330-20200828-00708

To evaluate the feasibility of the endoscopic transnasal approach (ETA) and to analyze the outcomes and factors of this surgical technique in the management of the tumor invading the anterior skull base.
A retrospective analysis was performed on 42 patients (31 males and 11 females, with mean age of 49 years) with sinonasal tumor invading the anterior skull base, who underwent ETA from June 2015 to April 2019 in Eye, Ear, Nose and Throat Hospital of Fudan University. Pathologically, there were 15 cases of squamous carcinoma (14 patients with T4bN0M0 and 1 patient with T4bN1M0) and 27 of olfactory neuroblastomas with Kadish stage C. Anterior skull base reconstruction was performed using the vascular pedicled nasoseptal mucoperiosteal flap and fascia lata. Brain non-contrast-enhanced CT was performed on the first postoperative day to exclude massive pneumocephalus, relevant brain edema and subarachnoid hemorrhage. Sinonasal contrast-enhanced MR was performed to assess the extent of the tumor removal. Kaplan-Mei