Tissue response to experimental dental cements prepared from a modified powder glass composition

• Published in: Dental materials journal Vol. 31; no. 4; pp. 583 - 592
• Main Authors: Boaventura, Juliana Maria Capelozza, Bertolini, Marcio José, Padovani, Gislaine Cristina, de Oliveira, Maria Rita Brancini, Zaghete, Maria Aparecida, de Oliveira Júnior, Osmir Batista, de Andrade, Marcelo Ferrarezi
• Format: Journal Article
• Language: English
• Published: Japan 2012
• Subjects: Aluminum Compounds; Animals; Biocompatible Materials; Calcium; Dentistry; Fluorides; Glass Ionomer Cements - chemistry; Glass Ionomer Cements - pharmacology; Male; Niobium; Powders - pharmacology; Rats; Silicon Compounds; Subcutaneous Tissue - drug effects
• ISSN: 1881-1361

The present work seeks to evaluate the biocompatibility of experimental glass ionomer cements (GIC) prepared from niobium-calcium fluoro-alumino-silicate glass powder and two commercial GICs. The GICs were implanted into the subcutaneous connective tissue of sixty rats. The rats were sacrificed during four varying time periods: 7, 15, 30, and 60 days and histopathological examinations were then performed. The Kruskal-Wallis test was performed to evaluate any significant differences between the materials. Additionally, multiple comparisons of the mean rank were also carried out using the Dunn test (p<0.05). No significant differences were observed that one GIC was superior to the other. The tissue response for all of the GICs tested was similar in all the periods examined.