Spread of new pandemic influenza A(H1N1)v virus in Russia

• Published in: Voprosy virusologiĭ Vol. 55; no. 3; p. 4
• Main Authors: L'vov, D K, Burtseva, E I, Shchelkanov, M Iu, Prilipov, A G, Kolobukhina, L V, Malyshev, N A, Bazarova, M V, Merkulova, L N, Deriabin, P G, Kuz'michev, A G, Fediakina, I T, Grebennikova, T V, Usachev, E V, Sadykova, G K, Shevchenko, E S, Trushakova, S V, Lavrishcheva, V V, Al'khovskiĭ, S, Samokhvalov, E I, Beliakova, N V, Ivanova, V T, Oskerko, T A, Latyshev, O E, Beliaev, A M, Beliaev, A L, Feodoritova, E L
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01-05-2010
• Subjects: Animals; Antiviral Agents - pharmacology; Cell Line; Chick Embryo; Disease Outbreaks; Dogs; Genome, Viral - genetics; Humans; Influenza A Virus, H1N1 Subtype - classification; Influenza A Virus, H1N1 Subtype - drug effects; Influenza A Virus, H1N1 Subtype - genetics; Influenza A Virus, H1N1 Subtype - isolation & purification; Influenza, Human - epidemiology; Influenza, Human - mortality; Influenza, Human - virology; Russia - epidemiology; Sequence Analysis, Protein; Russia
• ISSN: 0507-4088

The paper presents the results of the investigations of the development of a influenza A(H1N1)v pandemic, conducted by the D. I. Ivanovsky Research Institute of Virology, Russian Academy of Medical Sciences, and collaborating laboratories in the European part of Russia, in the Urals, Siberia, and in the Far East. In the prepandemic period (April 27 - June 11, 2009) its first diagnosis was established on May 21, 2009; the first strain was isolated on May 24, 2009; the data on complete genome sequencing were sent to the GenBank; the sensitivity of the strain to commercial antiviral commercial agents was studied. In the early pandemic period (June 11 - August 15), 73 patients who had come from 14 countries of Europe, America, and Asia were identified; 19 virus strains (partially or completely sequenced) were isolated. The pandemic period (August 15 - December 1) was marked by absolute dominance of pandemic influenza virus virtually in the absence of seasonal influenza; the first death caused by pandemic influenza was detected in late August; 3053 subjects were infected with the pandemic strain, as shown by polymerase chain reaction diagnosis; 202 strains were identified.