Surgical treatment of non-metastatic gastric GIST: two cases and review of the literature

Gastro-Intestinal Stromal Tumors (GISTs) represent an evolving field in oncological surgery and must be approached with specific prognostic and therapeutic criteria. In the GIST's suspicion the surgeon has to consider all the therapeutic possibilities, also for the impossibility to predict the...

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Bibliographic Details
Published in:	Il Giornale di chirurgia Vol. 31; no. 1-2; pp. 33 - 37
Main Authors:	Gheza, F, Pulcini, G, Cervi, E, Ferrari, A B, De Cesare, V, Cervi, G C
Format:	Journal Article
Language:	Italian
Published:	Italy 01-01-2010
Subjects:	Aged Aged, 80 and over Anastomosis, Surgical Female Gastrectomy - methods Gastrointestinal Hemorrhage - etiology Gastrointestinal Hemorrhage - surgery Gastrointestinal Stromal Tumors - complications Gastrointestinal Stromal Tumors - pathology Gastrointestinal Stromal Tumors - surgery Humans Stomach Neoplasms - complications Stomach Neoplasms - pathology Stomach Neoplasms - surgery Treatment Outcome
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Summary:	Gastro-Intestinal Stromal Tumors (GISTs) represent an evolving field in oncological surgery and must be approached with specific prognostic and therapeutic criteria. In the GIST's suspicion the surgeon has to consider all the therapeutic possibilities, also for the impossibility to predict the biological behaviour and the aggressiveness of the tumor. The presence of a GIST has to be suspected in patients observed for gastrointestinal bleeding, when another pathology isn't demostrable. Surgical strategy must consider a limited resection as the best treatment, differently from what we do for adenocarcinoma. The extension of the resection can changes, regarding tumor volume and position, from extremely invasive surgery to laparoscopic operations with a partial removal of the gastric wall. Lymphadenectomy is not indicated because these tumors rarely spread to the nodes. We present the clinical case of two patients observed for gastrointestinal bleeding and with preoperative diagnostic suspicion of GIST, submitted to surgical resection. In the first case we performed a superior polar gastrectomy with esofago-gastric anastomosis for the mass proximity to the cardias. In the second patient the intervention has been a limited resection of the fundus of stomach including the tumor.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Review-3 content type line 23 ObjectType-Case Study-5 ObjectType-Feature-1 ObjectType-Report-4
ISSN:	0391-9005