Electroporation and its application

Electroporation (EP) is a modern and versatile method that allows the penetration of macromolecules from the intercellular space into cells by forming the channels, under the influence of electromagnetic field. In addition to natural channels and pumps, building cell membranes, resulting electropore...

Full description

Saved in:

Bibliographic Details
Published in:	Polski merkuriusz lekarski Vol. 28; no. 168; p. 501
Main Authors:	Skołucka, Nina, Saczko, Jolanta, Kotulska, Małgorzata, Kulbacka, Julita, Choromańska, Anna
Format:	Journal Article
Language:	Polish
Published:	Poland 01-06-2010
Subjects:	Animals Cosmetic Techniques Drug Resistance, Multiple Drug Resistance, Neoplasm Electroporation - methods Genetic Therapy - methods Humans Neoplasms - therapy Photochemotherapy - methods
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Electroporation (EP) is a modern and versatile method that allows the penetration of macromolecules from the intercellular space into cells by forming the channels, under the influence of electromagnetic field. In addition to natural channels and pumps, building cell membranes, resulting electropores an additional way for the transport of macromolecules. The use of this phenomenon has brought good results as a complement to traditional therapeutic methods of treatment during application of cytostatics. EP combination with chemotherapy has reduced the need for surgical intervention (rescue authority). Electroporation is particularly useful for cancer with multidrug resistance, where the dose that enters the interior of cancer cells is limited. Electroporation was also used in transfection of nucleic acids, in photodynamic therapy, cosmetology, as well as the consolidation of the food.
ISSN:	1426-9686