N,N'-methyleno-didemnin A from the ascidian Trididemnum solidum. Complete NMR assignments and confirmation of the imidazolidinone ring by strategic analysis of 1J(CH)

The complete NMR assignments of N,N'-methyleno-didemnin A from Trididemnum solidum Van Name 1902 are reported along with a strategic analysis of (1)J(CH) coupling constants that confirm the presence of the imidazolidinone ring.

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Bibliographic Details
Published in:	Journal of natural products (Washington, D.C.) Vol. 74; no. 4; pp. 882 - 887
Main Authors:	Molinski, Tadeusz F, Ko, Jaeyoung, Reynolds, Kirk A, Lievens, Sarah C, Skarda, Katrina R
Format:	Journal Article
Language:	English
Published:	United States 25-04-2011
Subjects:	Animals Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Caribbean Region Depsipeptides - chemistry Depsipeptides - isolation & purification Depsipeptides - pharmacology Drug Screening Assays, Antitumor HCT116 Cells Humans Molecular Structure Nuclear Magnetic Resonance, Biomolecular Urochordata - chemistry
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Summary:	The complete NMR assignments of N,N'-methyleno-didemnin A from Trididemnum solidum Van Name 1902 are reported along with a strategic analysis of (1)J(CH) coupling constants that confirm the presence of the imidazolidinone ring.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1520-6025
DOI:	10.1021/np100846s