Portal embolization (an experimental-morphological study)

Results of experimental-morphological study of influence of unilobar portal embolization by biologic occlusive material RABROM on the liver of 6 laboratory animals are presented. It is shown that portal venous embolization leads to focal necrosis of parenchyma of embolized hepatic lobe, it atrophy a...

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Bibliographic Details
Published in:	Hirurgija (Moskva) no. 4; p. 35
Main Authors:	Nazarenko, N A, Vishnevskiĭ, V A, Skuba, N D, Vtiurin, B V, Buriev, I M, Chzhao, A V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 2001
Subjects:	Animals Atrophy Dogs Embolization, Therapeutic Hepatocytes - pathology Hepatocytes - physiology Humans Hypertrophy Liver - pathology Liver - ultrastructure Liver Regeneration Necrosis Portal Vein Preoperative Care Swine Time Factors
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Summary:	Results of experimental-morphological study of influence of unilobar portal embolization by biologic occlusive material RABROM on the liver of 6 laboratory animals are presented. It is shown that portal venous embolization leads to focal necrosis of parenchyma of embolized hepatic lobe, it atrophy and formation of portal cirrhosis. In non-embolized hepatic lobe the distinct signs of increased regeneration and hypertrophy of hepatocytes were revealed. RABROM didn't lead to damage and inflammatory changes of vascular wall that testifies to it biologic inertia. It is recommended to use the method of portal venous embolization for preparation of patients with low functional hepatic reserve for extensive resections.
ISSN:	0023-1207