New charge-deficient agmatine analogs

N,N'-Di-Boc-N"-triflylguanidine was demonstrated to be an efficient guanidinylation reagent for O-substituted hydroxylamines. N-(3-Aminooxypropyl)- and N-(3-aminopropoxy)guanidines, previously unknown isosteric and charge-deficient agmatine analogues, have been synthesized. The possibiliti...

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Bibliographic Details
Published in:	Bioorganicheskaia khimiia Vol. 31; no. 6; p. 645
Main Authors:	Simonian, A R, Grigorenko, N A, Vepsalainen, J, Khomutov, A R
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-2005
Subjects:	Agmatine - analogs & derivatives Agmatine - chemical synthesis Agmatine - chemistry
Online Access:	Get more information
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Summary:	N,N'-Di-Boc-N"-triflylguanidine was demonstrated to be an efficient guanidinylation reagent for O-substituted hydroxylamines. N-(3-Aminooxypropyl)- and N-(3-aminopropoxy)guanidines, previously unknown isosteric and charge-deficient agmatine analogues, have been synthesized. The possibilities of using these compounds in studying polyamine metabolism are discussed. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2005, vol. 31, no. 6; see also http://www.maik.ru.
ISSN:	0132-3423