Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus

The genes that were induced and suppressed in human embryonic kidney cell line RH upon the infection with tick-borne encephalitis virus were studied by the method of subtractive hybridization. The expression of interferon-induced genes IFI-54K and IFI-56K in the infected cells was found to increase...

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Bibliographic Details
Published in:	Bioorganicheskaia khimiia Vol. 29; no. 2; p. 175
Main Authors:	Gavrilov, B G, Monastyrskaia, G S, Velikodvorskaia, T V, Filiukova, O B, Konovalova, S N, Kachko, A A, Protopopova, E V, Nikolaev, L G, Loktev, V B, Sverdlov, E D
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-03-2003
Subjects:	Carrier Proteins Cells, Cultured Encephalitis Viruses, Tick-Borne - metabolism Encephalitis Viruses, Tick-Borne - pathogenicity Gene Expression Regulation Humans In Situ Hybridization - methods Kidney - cytology Kidney - embryology Kidney - physiology Kidney - virology Proteins - genetics Proteins - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Virus Cultivation
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Summary:	The genes that were induced and suppressed in human embryonic kidney cell line RH upon the infection with tick-borne encephalitis virus were studied by the method of subtractive hybridization. The expression of interferon-induced genes IFI-54K and IFI-56K in the infected cells was found to increase 50-100-fold.
ISSN:	0132-3423