Antimicrobial constituents of the leaves of Acalypha wilkesiana and Aacalypha hispida

An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside wer...

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Bibliographic Details
Published in:	Phytotherapy research Vol. 14; no. 5; pp. 371 - 374
Main Authors:	Adesina, S K, Idowu, O, Ogundaini, A O, Oladimeji, H, Olugbade, T A, Onawunmi, G O, Pais, M
Format:	Journal Article
Language:	English
Published:	England 01-08-2000
Subjects:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Euphorbiaceae - chemistry Glucosides - chemistry Humans Hydrolyzable Tannins Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Plant Extracts - chemistry Plant Extracts - pharmacology Plant Leaves - chemistry Plants, Medicinal - chemistry Tannins
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Summary:	An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside were also isolated from the inactive fraction of A. hispida. The structures were established by permethylation, 2D - NMR ((1)H and (13)C) and MS data.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0951-418X