The mechanisms of the neuroprotective action of carbonate mineral baths in ischemic brain lesions

Effects of Arzni effervescent mineral baths (EMB) on brain tissue metabolism were studied on white rats (normal controls and those with transitory cerebral ischemia). It was found that EMB prevent ischemia-related disorders of phospholipid and adeninnucleotide pools, promote an increase in vasoactiv...

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Published in:	Voprosy kurortologii, fizioterapii i lečebnoj fizičeskoj kulʹtury no. 1; p. 19
Main Authors:	Tunian, Iu S, Sekoian, E S, Karagezian, K G, Grigorian, R A, Manucharian, G G, Karagian, A T
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1999
Subjects:	Adenine Nucleotides - analysis Adenine Nucleotides - metabolism Adenosine - analysis Adenosine - metabolism Animals Armenia Baths - methods Brain - metabolism Brain Chemistry Brain Ischemia - metabolism Brain Ischemia - rehabilitation Carbonates - therapeutic use Disease Models, Animal Health Resorts Male Phospholipids - analysis Phospholipids - metabolism Prostaglandins - analysis Prostaglandins - metabolism Rats Armenia
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Summary:	Effects of Arzni effervescent mineral baths (EMB) on brain tissue metabolism were studied on white rats (normal controls and those with transitory cerebral ischemia). It was found that EMB prevent ischemia-related disorders of phospholipid and adeninnucleotide pools, promote an increase in vasoactive prostaglandins in brain tissue, shifts in catecholamines concentrations in the hemispheres and hypothalamus, inhibit the activity of monoaminoxidase and absorption of 3H-noradrenaline by brains sections. Mechanisms of neuroprotective action of Arzni EMB in cerebral ischemia are considered.
ISSN:	0042-8787