Merogony of Toxoplasma gondii (Apicomplexa: Coccidia) and its effect on the mortality and histopathology in the house mouse Mus musculus

Merogonic stages of Toxoplasma gondii, their effects on the mortality and histopathological changes in the orally-inoculated male house mice Mus musculus with low and high doses (LD&HD) of T. gondii sporulated oocysts was investigated. The mortality percentage in LD group was 16%, 20%, 28% and 7...

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Bibliographic Details
Published in:	Journal of the Egyptian Society of Parasitology Vol. 34; no. 1; p. 45
Main Authors:	Fayed, Hamed M, Allam, Kamilia A M, Ali, Nour-Eldin Shams-Eldin
Format:	Journal Article
Language:	English
Published:	Egypt 01-04-2004
Subjects:	Animals Brain - parasitology Brain - pathology Heart - parasitology Kidney - parasitology Kidney - pathology Lethal Dose 50 Liver - parasitology Liver - pathology Lung - parasitology Lung - pathology Male Mice Oocysts Random Allocation Spleen - parasitology Spleen - pathology Testis - parasitology Testis - pathology Toxoplasma - pathogenicity Toxoplasmosis, Animal - mortality Toxoplasmosis, Animal - pathology
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Summary:	Merogonic stages of Toxoplasma gondii, their effects on the mortality and histopathological changes in the orally-inoculated male house mice Mus musculus with low and high doses (LD&HD) of T. gondii sporulated oocysts was investigated. The mortality percentage in LD group was 16%, 20%, 28% and 72%, while that in HD group was 36%, 56%, 72% and 100% in the 1st-4th week, respectively. Meanwhile, the maximum mortality percentage of the control group reached 6%. The histopathological changes induced by the parasite in different organs such as kidneys, liver, brain, spleen, heart, lungs and testes were discussed.
ISSN:	1110-0583