Traumatic submacular hemorrhage treated with rt-PA and SF6

• Published in: Archivos de la Sociedad Española de Oftalmología Vol. 82; no. 8; p. 517
• Main Authors: Heras-Mulero, H, García-Gómez, P J, Sádaba-Echarri, L M, Salinas-Alamán, A, García-Layana, A
• Format: Journal Article
• Language: Spanish
• Published: Spain 01-08-2007
• Subjects: Adult; Eye Injuries - complications; Humans; Male; Retinal Hemorrhage - drug therapy; Retinal Hemorrhage - etiology; Sulfur Hexafluoride - administration & dosage; Sulfur Hexafluoride - therapeutic use; Time Factors; Tissue Plasminogen Activator - administration & dosage; Tissue Plasminogen Activator - therapeutic use; Treatment Outcome
• ISSN: 0365-6691

This patient was afflicted by a traumatic submacular hemorrhage. A posterior vitrectomy was performed and intravitreal rt-PA and SF6 were administered. Four weeks later, the visual acuity had increased from 0.1 to 0.8. No complications due to the treatment with rt-PA were reported.
It is known that waiting for the spontaneous blood removal in such cases results in a poor visual acuity recovery due to a toxic effect of the blood products. Both rt-PA and the SF6 are useful for the treatment of submacular hemorrhages secondary to age-related macular degeneration, and this case report has shown they are also useful to lyse traumatic blood clots, thus contributing to a better recovery of visual acuity.