Role of kallikrein-kinin system in pathogenesis of eye contusions

Studies of the plasma components of the kallikrein-kinin system (KKS) in the lacrimal fluid (LF) of damaged eyeball of 32 patients hospitalized for contusion for the eyeball showed an appreciable increase of KKS activity during the first three days and its less expressed increase on days 10-19 after...

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Bibliographic Details
Published in:	Vestnik oftal'mologii Vol. 115; no. 1; p. 18
Main Authors:	Bendelik, E K, Moshetova, L K, Iarovaia, G A, Dotsenko, V L, Neshkova, E A, Alekseev, I B, Tabekova, T T
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1999
Subjects:	Biomarkers Contusions - diagnosis Contusions - metabolism Eye - metabolism Eye Injuries - diagnosis Eye Injuries - metabolism Follow-Up Studies Humans Kallikrein-Kinin System - physiology Kallikreins - metabolism Prekallikrein - metabolism Tears - metabolism Trauma Severity Indices Wounds, Nonpenetrating - diagnosis Wounds, Nonpenetrating - metabolism
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Summary:	Studies of the plasma components of the kallikrein-kinin system (KKS) in the lacrimal fluid (LF) of damaged eyeball of 32 patients hospitalized for contusion for the eyeball showed an appreciable increase of KKS activity during the first three days and its less expressed increase on days 10-19 after the injury. The content of prekallikrein in the damaged eye LF depends on the severity of eye contusion and plasma KKS status, and the levels of LF prekallikrein in the damaged and intact eye correlate. Serum kallikrein activity depends on the severity of injury.
ISSN:	0042-465X