Assesment of the woman's age as a main predictive factor of assisted reproductive technology treatment outcome

• Published in: Akusherstvo i ginekologiia Vol. 45; no. 5; p. 22
• Main Authors: Timeva, T, Milachich, T, Petkova, L, Barov, D, Shterev, A
• Format: Journal Article
• Language: Bulgarian
• Published: Bulgaria 2006
• Subjects: Adult; Age Factors; Female; Humans; Maternal Age; Middle Aged; Pregnancy; Prognosis; Reproductive Techniques, Assisted - statistics & numerical data; Treatment Outcome
• ISSN: 0324-0959

Several factors could be used as a predictors of in vitro fertilization treatment outcome: female age, aetiology of sterility, previous ovarian surgery, embryo morphology and cleavage rates and also the technique of embryo transfer. The aim of the present study is to evaluate the role of the age to be used as a prognostic factor for the sterility treatment outcome. The tasks we assigned were to compare the several parameters: duration of the stimulation, number of retrieved oocytes, fertilization rate, implantation rate and clinical pregnancy rate after IVF/ICSI in different age's groups. The study results clearly demonstrate that in spite of decreasing number of retrieved oocytes after the age of 30, the fertilization rate remains elevated till 40 years. Regardless of this fact, the implantation rate and the clinical pregnancy rate were significantly lower after the age of 35. Reduction of the success rate in these cases showed that ART, despite of its renewals, is not the strategy for getting over the age in human reproduction.