Occurrence of primary aldosteronism in a group of ambulatory hypertensive patients

• Published in: Vnitřní lékar̆stvĭ Vol. 45; no. 1; p. 17
• Main Authors: Kreze, Jr, A, Okálová, D, Vanuga, P, Putz, Z, Kodaj, J, Hrnciar, J
• Format: Journal Article
• Language: Slovak
• Published: Czech Republic 01-01-1999
• Subjects: Humans; Hyperaldosteronism - complications; Hyperaldosteronism - diagnosis; Hyperaldosteronism - therapy; Hypertension - etiology
• ISSN: 0042-773X

Findings pertaining to the diagnosis and treatment of primary aldosteronism are rapidly expanding. In the present work the authors focused attention on the clinical application of some progressive methods. They examined a group of 115 ambulatory patients with arterial hypertension, not suspected of secondary arterial hypertension, in the course of one year. As a screening method of primary aldosteronism they selected the aldosterone renin ratio (ARR). Using this method the authors diagnosed 125 cases of primary aldosteronism, i.e. a 13% prevalence in the examined group. Only in one instance they detected an adenoma by computed tomography (CT), in the remaining patients, i.e. four times, the adenoma was verified by selective catheterization of adrenal veins and assessment of aldosterone and cortisol. The authors did not confirm a more accurate localization of the adenoma by the aldosterone/cortisol ration than when assessing aldosterone only. In two patients adrenalectomy was performed by laparoscopy and this surgical technique, as regards adrenal glands, was implemented for the first time in Slovakia in our department. It has certain advantages over classical adrenalectomy.