Arterial hypertension and ischemic heart disease: clinico-echocardiographic aspects

• Published in: Klinicheskaia meditsina Vol. 81; no. 11; p. 42
• Main Authors: Leshchinskiĭ, L A, Mul'tanovskiĭ, B L, Ponomarev, S B, Petrov, A G
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2003
• Subjects: Adult; Coronary Angiography; Data Interpretation, Statistical; Diastole; Echocardiography, Doppler; Humans; Hypertension - complications; Hypertension - physiopathology; Male; Middle Aged; Myocardial Ischemia - complications; Myocardial Ischemia - diagnostic imaging; Myocardial Ischemia - physiopathology; Ventricular Dysfunction, Left - physiopathology
• ISSN: 0023-2149

Doppler M-mode echocardiography was made in 156 males with ischemic heart disease (IHD) verified coronarographically. The patients were normotensive or had mild, moderate and severe arterial hypertension (AH) (groups 1, 2, 3 and 4, respectively). The groups were similar by functional anginal class. Echocardiographic findings were in many cases similar. This supports the hypothesis that IHD and AH are closely related. However, the addition of AH to atherosclerotic affection of the coronary artery or atherosclerosis rise in the presence of AH is associated with development of myocardial hypertrophy which is registered at echocardiography and correlates in severity with severity of AH. Myocardial hypertrophy is, on the one side, compensatory as it prevents dilation of the left ventricle and impairment of its contractility rising at later stage of the disease with depletion of the myocardial and coronary reserves, but, on the other side, it promotes diastolic dysfunction of the left ventricle, lowers its performance. The above phenomena are most pronounced in combination of IHD with severe AH. This combination presents a new qualitative state and, therefore, needs new approaches to its correction.