Intra-arterial chemotherapy of ORL cancer. Value of an implantable infusion system and scintigraphic monitoring

The technical difficulties and complications related to arterial catheterisation have inhibited the development of regional chemotherapy in ENT oncology despite the numerous theoretical advantages associated with this method. We report our recent experience with a completely implantable infusion sys...

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Bibliographic Details
Published in:	Annales d'oto-laryngologie et de chirurgie cervico-faciale Vol. 106; no. 8; p. 557
Main Authors:	Santini, J, Dassonville, O, Serra, C, Falewee, M N, Darcourt, J, Schneider, M, Demard, F
Format:	Journal Article
Language:	French
Published:	France 1989
Subjects:	Antineoplastic Combined Chemotherapy Protocols - administration & dosage Carcinoma, Squamous Cell - diagnostic imaging Carcinoma, Squamous Cell - drug therapy Cisplatin - administration & dosage Female Fluorouracil - administration & dosage Humans Infusion Pumps, Implantable Infusions, Intra-Arterial - instrumentation Male Middle Aged Otorhinolaryngologic Neoplasms - diagnostic imaging Otorhinolaryngologic Neoplasms - drug therapy Radionuclide Imaging Time Factors
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Summary:	The technical difficulties and complications related to arterial catheterisation have inhibited the development of regional chemotherapy in ENT oncology despite the numerous theoretical advantages associated with this method. We report our recent experience with a completely implantable infusion system; 12 systems were inserted, 11 unilateral and 1 bilateral. Treatment was carried out in 8 patients and the perfect biocompatibility of the material was confirmed. Good distribution of the infusion to the tumor zone and lack of cerebral diffusion were confirmed before treatment using an infusion of free Technetium.
ISSN:	0003-438X