Class I and II antigens and levels of IgG antibodies in patients with infiltrative tuberculosis of the lungs

Sixty patients with infiltrative tuberculosis of the lungs showing different dynamics of the process were examined. In the patients with unfavourable process of the disease antigens A2, B13, B16 and DR2 were more frequent than in the patients with favourable process of the disease in whom antigens A...

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Bibliographic Details
Published in:	Problemy tuberkuleza no. 3; p. 49
Main Authors:	Nikolaian, L T, Karapetian, E T, Pospelov, L E
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1989
Subjects:	Adult Female HLA Antigens - analysis HLA-A Antigens - analysis HLA-A2 Antigen HLA-B Antigens - analysis HLA-B13 Antigen HLA-C Antigens - analysis HLA-DR Antigens - analysis HLA-DR2 Antigen HLA-DR5 Antigen Humans Immunoglobulin G - analysis Male Prognosis Tuberculosis, Pulmonary - immunology
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Summary:	Sixty patients with infiltrative tuberculosis of the lungs showing different dynamics of the process were examined. In the patients with unfavourable process of the disease antigens A2, B13, B16 and DR2 were more frequent than in the patients with favourable process of the disease in whom antigens A9, B12, Cw4 and DR5 were more frequent. It suggested that the presence of antigen DR2 was a certain risk factor as to development of tuberculosis and its presence in tuberculous patients could indicate unfavourable outcome of the disease. The levels of the specific antituberculous antibodies to PPD were also indicative of favourable and unfavourable processes of pulmonary tuberculosis.
ISSN:	0032-9533