Blood myoglobin in children with progressive muscular dystrophy and in carriers

We studied the behaviour of serum myoglobin in 32 children affected by Duchenne muscular dystrophy, in 30 mothers (10 definite carriers and 20 possible carriers), in 5 sisters (possible carriers) and in 40 healthy women (control). The serum myoglobin was always increased in the patients affected by...

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Bibliographic Details
Published in:	Quaderni Sclavo di diagnostica clinica e di laboratorio Vol. 20; no. 4; p. 391
Main Authors:	Calandi, C, Baretti, S, Pacciani, G, Bagni, P, Borsotti, M, Tozzi, P, Adami Lami, C
Format:	Journal Article
Language:	Italian
Published:	Italy 01-12-1984
Subjects:	Adolescent Adult Carrier State - blood Carrier State - enzymology Child Child, Preschool Creatine Kinase - metabolism Female Humans Isoenzymes Male Middle Aged Muscular Dystrophies - blood Muscular Dystrophies - enzymology Myoglobin - blood
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Summary:	We studied the behaviour of serum myoglobin in 32 children affected by Duchenne muscular dystrophy, in 30 mothers (10 definite carriers and 20 possible carriers), in 5 sisters (possible carriers) and in 40 healthy women (control). The serum myoglobin was always increased in the patients affected by Duchenne muscular dystrophy; the greatest values were in the patients who were still ambulant, with a behaviour similar to creatine kinase. In the carriers the myoglobinemia showed a significant increase in definite carriers, while there was no significant difference between the possible carriers and the controls.
ISSN:	0033-4979