Effect of phosphemide in combination with dexamethasone on DNA structure in sarcoma 45

It is shown that under the influence of phosphemide in combination with dexamethasone some characteristics of tumour DNA (content of 5 methyl cytosine, temperature, interval and enthalpy of melting) approximate the corresponding characteristics of DNA of healthy animals' liver better than under...

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Bibliographic Details
Published in:	Biofizika Vol. 30; no. 3; p. 414
Main Authors:	Babaian, Iu S, Aslanian, L L, Ananian, G V, Garibian, D V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-05-1985
Subjects:	5-Methylcytosine Animals Antineoplastic Agents - pharmacology Aziridines - pharmacology Azirines - pharmacology Cytosine - analogs & derivatives Cytosine - metabolism Dexamethasone - pharmacology DNA, Neoplasm - metabolism DNA, Single-Stranded - metabolism Drug Synergism Male Rats Sarcoma, Experimental - metabolism Viscosity
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Summary:	It is shown that under the influence of phosphemide in combination with dexamethasone some characteristics of tumour DNA (content of 5 methyl cytosine, temperature, interval and enthalpy of melting) approximate the corresponding characteristics of DNA of healthy animals' liver better than under the influence of phosphemide only.
ISSN:	0006-3029