Vasculitis complicating treatment with streptokinase: delayed allergic reaction

The authors report a case of vascular purpura occurring eleven days after the injection of streptokinase for a myocardial infarction. This adverse event falls within a context of hypersensitivity vasculitis (type III). In this particular case, imputation to the thrombolytic agent was established by...

Full description

Saved in:

Bibliographic Details
Published in:	Annales de cardiologie et d'angéiologie Vol. 42; no. 3; p. 139
Main Authors:	Yvorra, S, Desfossez, L, Broin, P, Disdier, P, Jean-Pastor, M J, Bory, M
Format:	Journal Article
Language:	French
Published:	France 01-03-1993
Subjects:	Aged Humans Hypersensitivity, Delayed Male Purpura, Schoenlein-Henoch - chemically induced Purpura, Schoenlein-Henoch - diagnosis Purpura, Schoenlein-Henoch - immunology Streptokinase - adverse effects Streptokinase - immunology
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The authors report a case of vascular purpura occurring eleven days after the injection of streptokinase for a myocardial infarction. This adverse event falls within a context of hypersensitivity vasculitis (type III). In this particular case, imputation to the thrombolytic agent was established by the official method for the imputation of adverse or toxic effects of drugs. Routine renal function studies were normal. The outcome was satisfactory following rest only but the existence of a mixed cryoglobulinemia, responsible secondarily for cold-related distal ischemic symptomatology of the lower limbs led to the successful prescription of a short course of corticosteroids.
ISSN:	0003-3928