Effect of 2-pyrrolidone and gamma-butyrolactone on the rate of 14C-leucine incorporation into the proteins of different brain structures and of their arterial tissues

The ability of cyclic GABA and GHBA derivatives--2-pyrrolidone and gamma-butyrolactone--to increase markedly the inclusion of 14C-leucine in the proteins of hypothalamus and cerebral arteries both normally and in condition of cerebral blood supply disturbances produced by unilateral 20 min ligation...

Full description

Saved in:

Bibliographic Details
Published in:	Biulleten' eksperimental'noi biologii i meditsiny Vol. 106; no. 11; p. 571
Main Authors:	Mirzoian, S A, Zalinian, M G, Gevorkian, G A, Topchian, A V, Balasanian, M G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-1988
Subjects:	4-Butyrolactone - pharmacology Animals Brain - drug effects Brain - metabolism Carbon Radioisotopes Cerebral Arteries - drug effects Cerebral Arteries - metabolism Furans - pharmacology Hypoxia, Brain - metabolism Leucine - metabolism Nerve Tissue Proteins - biosynthesis Pyrrolidinones - pharmacology Rats
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The ability of cyclic GABA and GHBA derivatives--2-pyrrolidone and gamma-butyrolactone--to increase markedly the inclusion of 14C-leucine in the proteins of hypothalamus and cerebral arteries both normally and in condition of cerebral blood supply disturbances produced by unilateral 20 min ligation of a common carotid artery has been demonstrated.
ISSN:	0365-9615