The coupling of phosphoinositide metabolism sensitive to ACTH with the adenylate cyclase system in the synaptosomes

The effect of cAMP on the phosphoinositide metabolism increased by the ACTH, was studied in the rat brain synaptosomes. The data obtained suggest that a coupling of the phosphoinositide metabolism and the adenylate cyclase system occurs under these conditions.

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Bibliographic Details
Published in:	Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova Vol. 78; no. 11; p. 125
Main Author:	Pavlinova, L I
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-1992
Subjects:	1-Methyl-3-isobutylxanthine - pharmacology Adenylyl Cyclases - physiology Adrenocorticotropic Hormone - pharmacology Animals Brain - drug effects Brain - metabolism Calcium - metabolism Cyclic AMP - pharmacology Dose-Response Relationship, Drug Drug Interactions Male Phosphatidylinositols - metabolism Rats Second Messenger Systems - drug effects Second Messenger Systems - physiology Synaptosomes - drug effects Synaptosomes - metabolism
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Summary:	The effect of cAMP on the phosphoinositide metabolism increased by the ACTH, was studied in the rat brain synaptosomes. The data obtained suggest that a coupling of the phosphoinositide metabolism and the adenylate cyclase system occurs under these conditions.
ISSN:	0015-329X