In vivo tritium contamination effects on water exchange across the erythrocyte membranes: a nuclear magnetic resonance study

The effects produced by chronic in vivo tritium contamination on the process of water diffusion across the rat erythrocyte membranes were investigated using an NMR relaxation method. As the level of tritium intake increased, an inhibition of the water permeability was observed, reaching values of 40...

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Bibliographic Details
Published in:	Biochimica et biophysica acta Vol. 1065; no. 1; p. 99
Main Authors:	Petcu, I, Lupu, M, Grosescu, R
Format:	Journal Article
Language:	English
Published:	Netherlands 31-05-1991
Subjects:	Animals Cell Membrane Permeability Diffusion Erythrocyte Membrane - metabolism Magnetic Resonance Spectroscopy - methods Male Rats Rats, Inbred Strains Thermodynamics Tritium Water
Online Access:	Get more information
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Summary:	The effects produced by chronic in vivo tritium contamination on the process of water diffusion across the rat erythrocyte membranes were investigated using an NMR relaxation method. As the level of tritium intake increased, an inhibition of the water permeability was observed, reaching values of 40% for corresponding absorbed doses of about 100 mGy. The activation energy of the transport process was also significantly increased, suggesting that the mechanism of the water diffusion across the membrane had changed.
ISSN:	0006-3002