The neuronal activity of the ventromedial hypothalamus during pharmacological exposures that modulate motivational and emotional states

Neuronal activity of the ventromedial hypothalamus was studied in food- and water-deprived, saturated unrestrained rats and after i. p. administrations of alcohol, nembutal, 5-HT and disulphiram. The neurons whose activity did not depend on motivational states decreased their firing rate. The data o...

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Bibliographic Details
Published in:	Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova Vol. 78; no. 10; p. 29
Main Authors:	Gasanov, G G, Kuliev, E I
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-10-1992
Subjects:	5-Hydroxytryptophan - pharmacology Animals Disulfiram - pharmacology Electrodes, Implanted Emotions - drug effects Emotions - physiology Ethanol - pharmacology Food Deprivation - physiology Male Membrane Potentials - drug effects Membrane Potentials - physiology Motivation Neurons - drug effects Neurons - physiology Pentobarbital - pharmacology Rats Time Factors Ventromedial Hypothalamic Nucleus - drug effects Ventromedial Hypothalamic Nucleus - physiology Water Deprivation - physiology
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Summary:	Neuronal activity of the ventromedial hypothalamus was studied in food- and water-deprived, saturated unrestrained rats and after i. p. administrations of alcohol, nembutal, 5-HT and disulphiram. The neurons whose activity did not depend on motivational states decreased their firing rate. The data obtained suggests that motivational and emotional effects of the ventromedial hypothalamus are based on various cell mechanisms.
ISSN:	0015-329X