Effect of ginseng preparations on the activity of identified neurons of Heliz lucorum snails

It has been demonstrated that the effects of aqueous extracts from the native ginseng and extracts of genseng tissue culture on the activity of identified neurones are identical. Neuronal excitability, tested intracellularly, significantly increases to the 60th minute of drug application, whereas gr...

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Bibliographic Details
Published in:	Žurnal ėvolûtsionnoj biohimii i fiziologii Vol. 16; no. 2; p. 154
Main Authors:	Balaban, P M, Andreev, S Iu, Saakian, S A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-03-1980
Subjects:	Animals Culture Techniques Electric Stimulation Helix (Snails) Membrane Potentials - drug effects Neurons - drug effects Panax Periodicity Plant Extracts - pharmacology Plants, Medicinal Synaptic Transmission - drug effects
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Summary:	It has been demonstrated that the effects of aqueous extracts from the native ginseng and extracts of genseng tissue culture on the activity of identified neurones are identical. Neuronal excitability, tested intracellularly, significantly increases to the 60th minute of drug application, whereas gradually developing depolarization simultaneously disappears. Rhythmic orthodromic stimulation revealed the increase in neuronal responses during ginseng perfusion, the synaptic efficiency remaining constant. It is suggested that changes in transmembrane potential level evoked by administration of ginseng preparations are not related to changes in the excitability. Changes in the adaptive capacities of the neurones in invertebrate animals are due to nonspecific endoneuronal shifts in cellular metabolism induced by ginseng administation.
ISSN:	0044-4529