Synaptosome membrane proteins of the rat brain in convulsions caused by increased oxygen pressure

High oxygen pressure (0.7 MPa during 30-40 min) increased the quantity of high molecular proteins with simultaneous decrease in amount of low molecular proteins in rat brain synaptosomes. At the same time, the significant increase of lipoprotein fluorescence with emission at 435 nm was observed. Oxy...

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Bibliographic Details
Published in:	Voprosy meditsinskoi khimii Vol. 32; no. 4; p. 35
Main Authors:	Sherstnev, K B, Suleĭmanov, A K
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-1986
Subjects:	Animals Brain - metabolism Electrophoresis, Disc Female Hyperbaric Oxygenation - adverse effects Male Membrane Proteins - metabolism Molecular Weight Rats Seizures - etiology Seizures - metabolism Spectrometry, Fluorescence Synaptic Membranes - metabolism
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Summary:	High oxygen pressure (0.7 MPa during 30-40 min) increased the quantity of high molecular proteins with simultaneous decrease in amount of low molecular proteins in rat brain synaptosomes. At the same time, the significant increase of lipoprotein fluorescence with emission at 435 nm was observed. Oxygen at high pressure inhibited incorporation of 14C-leucine into synaptosomal membrane proteins. Possible mechanisms of these alterations are discussed.
ISSN:	0042-8809