Plasmapheresis in the treatment of patients with hypertension

• Published in: Sovetskaia meditsina no. 10; p. 20
• Main Authors: Ananchenko, V G, Kuznetsov, S V, Alizade, I G, Karaeva, N T
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 1991
• Subjects: Antihypertensive Agents - administration & dosage; Blood Pressure - drug effects; Blood Pressure - physiology; Combined Modality Therapy; Drug Resistance; Humans; Hypertension - physiopathology; Hypertension - therapy; Plasmapheresis; Vascular Resistance - drug effects; Vascular Resistance - physiology
• ISSN: 0038-5077

The authors discuss the results of the use of plasmapheresis in multimodality treatment of patients with stage II essential hypertension. At present the prevalence, ever increasing accessibility and relative simplicity of plasmapheresis make it possible to use it for the treatment of essential hypertension. Analysis of the data obtained shows the high efficacy of plasmapheresis in essential hypertension. Since plasmapheresis turned out effective in combination with drug therapy and alone as well, it is concluded that plasmapheresis is not only an approach to overcoming resistance to hypotensive therapy but also an independent treatment modality that exerts a considerable effect on the immunologic and hemorheologic blood properties. The above-indicated allows recommending plasmapheresis for the treatment of patients suffering from essential hypertension, since it may lead to a long-term decrease of arterial pressure, to the enhancement of the sensitivity to hypotensive drugs, to the diminution of drug requirements, thereby ameliorating the course and prognosis of the disease in patients suffering from essential hypertension.