Dynamics of early postradiation changes in capillary endothelium (quantitative electron microscopic analysis

Oedema, breakage and fragmentation of plasmolemma and mitochondrial damages developed in rats 1-48 h following total-body X-irradiation (4.5 Gy). These changes were most pronounced 2-6 h after exposure, when they spread over 20-30% of the population, and accompanied by the appearance of wide gaps in...

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Bibliographic Details
Published in:	Radiobiologiia Vol. 23; no. 2; p. 196
Main Authors:	Stepanov, R P, Dubrovskaia, V F
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-03-1983
Subjects:	Animals Capillaries - radiation effects Endothelium - radiation effects Microscopy, Electron Mitochondria - radiation effects Rats Time Factors
Online Access:	Get more information
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Summary:	Oedema, breakage and fragmentation of plasmolemma and mitochondrial damages developed in rats 1-48 h following total-body X-irradiation (4.5 Gy). These changes were most pronounced 2-6 h after exposure, when they spread over 20-30% of the population, and accompanied by the appearance of wide gaps in the endothelial layer and maximal accretion of free lipids in the endotheliocyte cytoplasm. Changes in the sizes and number of mitochondria were responsible for the tendency toward the increase in their relative total volume which was most pronounced after 12 h.
ISSN:	0033-8192