Changes in the structuro-functional properties of erythrocytes in vascular diseases of the brain

In patients with various impairments of brain circulation a decrease in deformation and osmotic stability of erythrocytes were observed. These findings correlated with the decrease in activity of Na+, K+- and Ca2+-ATPases from the cell membranes. At the same time, the Mg/+-ATPase activity was marked...

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Bibliographic Details
Published in:	Voprosy meditsinskoi khimii Vol. 27; no. 4; p. 486
Main Authors:	Mkheian, E E, Tunian, Iu S, Akopov, S E, Badzhinian, S A, Bakunts, G O
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1981
Subjects:	Calcium-Transporting ATPases - metabolism Cerebral Infarction - blood Erythrocyte Membrane - physiology Erythrocytes - enzymology Hemolysis Humans Hydrogen-Ion Concentration Hypertension - blood Ischemic Attack, Transient - blood Lipid Bilayers Middle Aged Sodium-Potassium-Exchanging ATPase - metabolism
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Summary:	In patients with various impairments of brain circulation a decrease in deformation and osmotic stability of erythrocytes were observed. These findings correlated with the decrease in activity of Na+, K+- and Ca2+-ATPases from the cell membranes. At the same time, the Mg/+-ATPase activity was markedly increased. Conductivity for K+, Na+ and Ca2+ was increased in lipid bilayer of erythrocytes obtained from the patients with brain vascular pathology.
ISSN:	0042-8809