Effects of polyunsaturated fatty acids in the ration on the structure of peripheral lymphoid organs, immunological parameters and nonspecific resistance of rats

It has been established that the fatty component of the ration, with the rest ingredients being unchanged, alters the immunologic status of the body. When fatty portion of the ration was substituted for sunflower oil (omega 6) active macrophage-plasmocytic reaction in the lymphoid organs, elevation...

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Bibliographic Details
Published in:	Voprosy pitaniia no. 2; p. 42
Main Authors:	Trushina, E N, Sergeeva, K V, Volgarev, M N, Levachev, M M, Tokareva, T V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-03-1992
Subjects:	Animals Antibody Formation - drug effects Dietary Fats, Unsaturated - pharmacology Fatty Acids, Unsaturated - pharmacology Fish Oils - pharmacology Lymph Nodes - drug effects Male Plant Oils - pharmacology Rats Rats, Inbred Strains Spleen - drug effects Sunflower Oil T-Lymphocytes - drug effects T-Lymphocytes - immunology
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Summary:	It has been established that the fatty component of the ration, with the rest ingredients being unchanged, alters the immunologic status of the body. When fatty portion of the ration was substituted for sunflower oil (omega 6) active macrophage-plasmocytic reaction in the lymphoid organs, elevation of the humoral immunity parameters and suppression of the T-cell system were recorded. The reaction to immunization was less pronounced when equal ratios of sunflower and ichtyenic oils were used. When the fatty component of the ration was completely substituted for ichtyenic oil, a decrease in T-lymphocyte number and focal necrotic changes in the lymphoid organs were observed. The fatty component of the rations used produced no significant effect on the bactericidal activity of the blood serum.
ISSN:	0042-8833