Genetic markers of erythrocyte blood groups in multiple sclerosis among the Armenian population

The isoserologic systems, including AB, Rh-Hz, MNSs, Duffy, Kidd, Kell-Chellano, Lutheran, Diego, and Lewis ones were investigated in 50 patients with disseminated sclerosis and in the general population. An increased rate of the Duffy phenotype (a-b+) is reported in the patients versus the populati...

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Bibliographic Details
Published in:	Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) Vol. 83; no. 3; p. 42
Main Authors:	Darbinian, V Zh, Nersisian, V M, Martirosian, I G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1983
Subjects:	ABO Blood-Group System Adolescent Adult Armenia Blood Group Antigens Duffy Blood-Group System Female Genetic Markers Humans Kell Blood-Group System Kidd Blood-Group System Male Middle Aged Multiple Sclerosis - blood Rh-Hr Blood-Group System Risk Armenia
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Summary:	The isoserologic systems, including AB, Rh-Hz, MNSs, Duffy, Kidd, Kell-Chellano, Lutheran, Diego, and Lewis ones were investigated in 50 patients with disseminated sclerosis and in the general population. An increased rate of the Duffy phenotype (a-b+) is reported in the patients versus the population control. Individuals with this phenotype are at three times as great a risk of developing disseminated sclerosis than those with the Duffy phenotype (a+b-). The Duffy antigen (b+) is considered as a possible genetic marker of the disease in the Armenian population.
ISSN:	0044-4588