Thermoregulatory uncoupling of oxidation and phosphorylation in the chick brain in embryogenesis

The cooling of hen incubated eggs to 28 degrees C brings to disconnection of oxidative phosphorylation in brain on the 12th day of development. The addition of DNP (5 x 10(-5) M) takes off the cooling effect.

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Bibliographic Details
Published in:	Ukrainskij biohimičeskij žurnal Vol. 64; no. 5; p. 106
Main Authors:	Simonian, A A, Stepanian, R A, Badalian, R B
Format:	Journal Article
Language:	Russian
Published:	Ukraine 01-09-1992
Subjects:	2,4-Dinitrophenol Adenosine Triphosphatases - drug effects Adenosine Triphosphatases - metabolism Animals Body Temperature Regulation - drug effects Body Temperature Regulation - physiology Brain - drug effects Brain - embryology Brain - physiology Chick Embryo Cold Temperature Dinitrophenols - pharmacology Mitochondria - drug effects Mitochondria - physiology Oxidative Phosphorylation - drug effects Uncoupling Agents - pharmacology
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Description
Summary:	The cooling of hen incubated eggs to 28 degrees C brings to disconnection of oxidative phosphorylation in brain on the 12th day of development. The addition of DNP (5 x 10(-5) M) takes off the cooling effect.
ISSN:	0201-8470