Morphological changes in the neuroendocrine system during experimental infection of animals with L-forms of group B Streptococcus

White rats and mice were subjected to a single intraperitoneal inoculation with a stable L-form of Streptococcus B (strain 090). The hypothalamus, hypophysis and adrenal cortex of the animals were subsequently studied during one year. Progressive degenerative, inflammatory, necrotic and sclerotic ch...

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Bibliographic Details
Published in:	Arkhiv patologii Vol. 49; no. 5; p. 64
Main Authors:	Khostikian, N G, Vartazarian, N D, Gorina, L G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1987
Subjects:	Animals Hypothalamo-Hypophyseal System - microbiology Hypothalamo-Hypophyseal System - pathology L Forms Mice Necrosis Pituitary-Adrenal System - microbiology Pituitary-Adrenal System - pathology Rats Streptococcal Infections - microbiology Streptococcal Infections - pathology Streptococcus agalactiae
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Summary:	White rats and mice were subjected to a single intraperitoneal inoculation with a stable L-form of Streptococcus B (strain 090). The hypothalamus, hypophysis and adrenal cortex of the animals were subsequently studied during one year. Progressive degenerative, inflammatory, necrotic and sclerotic changes found in the system hypothalamus-hypophysis-adrenals were due to the bacteria persistence in these organs leading to the disturbance of hormonal homeostasis and development of the system deficiency. There was also the tendency (in 6-12 months after the inoculation) to intensifying regeneration with partial recovery of the organs function.
ISSN:	0004-1955