Alanine aminotransferase--a surrogate marker of viral hepatitis

Examinations of 4457 blood donors (about 80% were men aged 18 to 30) revealed an increased level of serum glutamic-pyruvic transaminase (SGPT) in 82 (1.8%). Specific markers of viral hepatitis C were detected in 15.9%, of hepatitis B in 12.0%, of hepatitis D in 2.0%, of hepatitis E in 8.0%, of hepat...

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Bibliographic Details
Published in:	Voprosy virusologiĭ Vol. 40; no. 1; p. 25
Main Authors:	Zhiburt, E B, Bel'gesov, N V, Vashchenko, T N, Bondarenko, I G, Tokmakov, V S, Vasiliuk, V B
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1995
Subjects:	Adolescent Adult Alanine Transaminase - analysis Biomarkers - analysis Hepatitis - enzymology Humans Male
Online Access:	Get more information
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Summary:	Examinations of 4457 blood donors (about 80% were men aged 18 to 30) revealed an increased level of serum glutamic-pyruvic transaminase (SGPT) in 82 (1.8%). Specific markers of viral hepatitis C were detected in 15.9%, of hepatitis B in 12.0%, of hepatitis D in 2.0%, of hepatitis E in 8.0%, of hepatitis A in 2.0% of sera with high SGPT levels. Mandatory screening of blood donors revealed specific markers of viral hepatitis in 15.9% of cases, additional testing detected these markers in 10.9% cases more. A conclusion is made that an increase of SGPT activity is an independent surrogate marker of viral hepatitis.
ISSN:	0507-4088