Parasympathetic regulation of cardiac rhythm in delta sleep-inducing peptide deficiency

The effect of delta-sleep peptide (DSP) deficiency on the parasympathetic regulation of the heart rate was studied on 35 rabbits. It was established that the injection of an-serum (titer-1:2000-1:3000) leads to the attenuation of parasympathetic influences: heart rate increase in freely behaving ani...

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Bibliographic Details
Published in:	Biulleten' eksperimental'noi biologii i meditsiny Vol. 104; no. 7; p. 3
Main Authors:	Zviagintseva, M A, Kosharskaia, I L, Badikov, V I, Beskrovnova, N N, Ul'ianinskiĭ, L S
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-1987
Subjects:	Animals Delta Sleep-Inducing Peptide - deficiency Delta Sleep-Inducing Peptide - immunology Electric Stimulation Heart Rate - drug effects Immune Sera - pharmacology Immunization Myocardium - ultrastructure Parasympathetic Nervous System - drug effects Parasympathetic Nervous System - physiology Rabbits Vagus Nerve - physiology
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Summary:	The effect of delta-sleep peptide (DSP) deficiency on the parasympathetic regulation of the heart rate was studied on 35 rabbits. It was established that the injection of an-serum (titer-1:2000-1:3000) leads to the attenuation of parasympathetic influences: heart rate increase in freely behaving animals and a decrease in negative chronotropic effect with direct vagus irritation. Antiserum, like DSP, administration causes practically no damage of the myocardial ultrastructure.
ISSN:	0365-9615