Ratio of amylase clearance and creatinine clearance in the diagnosis of acute pancreatitis

In 21 healthy volunteers the ratio of amylase clearance and creatinine clearance (Cam/Ccr) was determined in urine collected at admission, after a 1-hour collection period and after a 2-hour collection period. The normal values were 1.8 +/- 1.6%, 1.9 +/- 2% and 2.0 +/- 1.7% respectively. They were c...

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Bibliographic Details
Published in:	Schweizerische medizinische Wochenschrift Vol. 111; no. 22; p. 806
Main Authors:	Haffter, D, Reichlin, B, Gyr, K
Format:	Journal Article
Language:	German
Published:	Switzerland 30-05-1981
Subjects:	Acute Disease Amylases - urine Creatinine - urine Humans Metabolic Clearance Rate Pancreatitis - diagnosis Pancreatitis - metabolism
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Summary:	In 21 healthy volunteers the ratio of amylase clearance and creatinine clearance (Cam/Ccr) was determined in urine collected at admission, after a 1-hour collection period and after a 2-hour collection period. The normal values were 1.8 +/- 1.6%, 1.9 +/- 2% and 2.0 +/- 1.7% respectively. They were comparable with those published by others. The reproducibility of the method was acceptable (r = 0.62). When compared with serum amylase determinations, Cam/Ccr showed neither better sensitivity in 19 patients suffering an acute episode of proven pancreatitis, nor better specificity in 19 patients with acute abdomen but no evidence of pancreatitis.
ISSN:	0036-7672