Channel-forming properties of Steatoda paykulliana spider venom

While studying Steatoda paykulliana spider venom interaction with bilayer lipid membranes (BLM) it was shown that venom formed ionic channels permeable for bi- and monovalent cations. The selectivity of these channels was determined. It was found that their living time in open state depended on the...

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Bibliographic Details
Published in:	Biofizika Vol. 29; no. 4; p. 620
Main Authors:	Sokolov, Iu V, Chanturiia, A N, Lishko, V K
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-1984
Subjects:	Arthropod Venoms - pharmacology Cadmium - metabolism Ion Channels - metabolism Lipid Bilayers - metabolism Membrane Potentials Spider Venoms - pharmacology
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Summary:	While studying Steatoda paykulliana spider venom interaction with bilayer lipid membranes (BLM) it was shown that venom formed ionic channels permeable for bi- and monovalent cations. The selectivity of these channels was determined. It was found that their living time in open state depended on the membrane potential. It was stated that cadmium ions were the effective blockers of investigated channels. The properties of these channels could be compared with those produced by latrotoxin in BLM.
ISSN:	0006-3029