A pharmacological analysis of the GABA-ergic system of the primordial hippocampus in the frog Rana temporaria

The data on evoked potentials (EP) in the frog primordial hippocampus during the surface application of gamma-aminobutyric acid (GABA), beta-alanine and aminooxyacetic acid in the region of EP recording are presented. These results in the aggregate with the earlier described effects of picrotoxin, b...

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Bibliographic Details
Published in:	Nauchnye doklady vysshei shkoly. Biologicheskie nauki no. 9; p. 82
Main Authors:	Trepakov, V V, Saakian, S A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1991
Subjects:	Animals Dose-Response Relationship, Drug Evoked Potentials - drug effects Evoked Potentials - physiology Hippocampus - drug effects Hippocampus - physiology Neural Inhibition - drug effects Neural Inhibition - physiology Rana temporaria Receptors, GABA-A - drug effects Receptors, GABA-A - physiology Time Factors
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Summary:	The data on evoked potentials (EP) in the frog primordial hippocampus during the surface application of gamma-aminobutyric acid (GABA), beta-alanine and aminooxyacetic acid in the region of EP recording are presented. These results in the aggregate with the earlier described effects of picrotoxin, bicuculline, muscimol, baclofen (on EP) and GABA (on intracellular potentials) permit to suggest the presence of GABA-ergic inhibitory system and two types of GABA receptors in the frog primordial hippocampus.
ISSN:	0470-4606