Significance of gastrointestinal microflora for the metabolism of foreign compounds

Microbiological biotransformation as a part of metabolism of foreign compounds in general, has great toxicological consequences. An overview on the most important types of reactions is given. In detail, comparative investigations of the metabolism of gamma-HCH, azobenzene and progoitrin in germfree...

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Bibliographic Details
Published in:	Die Nahrung Vol. 31; no. 5-6; p. 619
Main Authors:	Kujawa, M, Macholz, R, Schulze, J, Schnaak, W
Format:	Journal Article
Language:	German
Published:	Germany 1987
Subjects:	Animals Antithyroid Agents - metabolism Azo Compounds - metabolism Bacteria - metabolism Biotransformation Cecum - metabolism Digestive System - microbiology Feces - analysis Germ-Free Life Glucosinolates - metabolism Lindane - metabolism Polychlorinated Biphenyls - metabolism Rats
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Summary:	Microbiological biotransformation as a part of metabolism of foreign compounds in general, has great toxicological consequences. An overview on the most important types of reactions is given. In detail, comparative investigations of the metabolism of gamma-HCH, azobenzene and progoitrin in germfree and conventionalized rats are described and results from the literature are presented.
ISSN:	0027-769X