Multiple applications of closed permanent wet dressings. Their mode of action

• Published in: Medicina cutánea ibero-latino-americana Vol. 9; no. 1; p. 67
• Main Authors: Mirande, L M, Landolfi, J M, Pedemonte, L H
• Format: Journal Article
• Language: Spanish
• Published: Portugal 1981
• Subjects: Adrenal Cortex Hormones - administration & dosage; Anti-Bacterial Agents - administration & dosage; Bandages; Borates - administration & dosage; Drug Combinations; Humans; Hydrogen-Ion Concentration; Ointments; Skin Diseases - therapy
• ISSN: 0210-5187

New applications and forms of Darier's humid permanent closed cures are analysed specially in connection with concepts of cutaneous hydratation. The multiplicity of their application however makes it necessary to find an explanation for their excellent effects which are probably related to the anti-inflammatory, antipruritic and antiinfectious actions as well as the permanent draining effect from the deeper layers to the surface of the epidermis. The hydratation affected by HPCC is very important in dry and exudative stasis dermatitis with both a complete or a partial loss of stratum corneum. Cutaneous eutrophia is restored quite rapidly and an anti-infectious effect is brought about simultaneously. Especially in cases of stasis dermatitis with excessive secretions and pus formation the permanent drainage and hydratation make possible rapid healing. The preference for sodium borate does not exclude the use of other substance both alone or in combination. On the contrary, HPCC may be employed with especific antibiotics. Topical corticosteroid and antibiotic combination is frequently used in stasis dermatitis. In cases of pyoderma, the results obtained are definitively better when antibiotics are of the treatment. Eventually systematic corticoids may be included in the therapeutic arsenal.