Quantitative changes in the nucleic acid nuclear fraction of rat brain cells following removal of the superior cervical sympathetic ganglion

Quantitative changes in the nucleic acid nuclear fraction of rat brain cells following removal of the superior cervical sympathetic ganglion

The nucleic acid content of the nuclear fraction of cerebral hemispheres was studied 1, 3, 7, 20 and 90 days after unilateral removal of superior cervical ganglion. The results obtained indicate that the content of nuclear RNA is significantly reduced in the desympathized side 1 day after removal of...

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Bibliographic Details
Published in:Voprosy biokhimii mozga Vol. 9; p. 181
Main Authors: Mkheian, E E, Karapetian, T D
Format: Journal Article
Language:Russian
Published: Armenia (Republic) 1974
Subjects:
Animals
Brain - ultrastructure
Brain Chemistry
Cell Nucleus - analysis
DNA - analysis
Female
Ganglia, Autonomic - physiology
Male
Rats
RNA - analysis
Sympathectomy
Time Factors
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Summary:The nucleic acid content of the nuclear fraction of cerebral hemispheres was studied 1, 3, 7, 20 and 90 days after unilateral removal of superior cervical ganglion. The results obtained indicate that the content of nuclear RNA is significantly reduced in the desympathized side 1 day after removal of the ganglion. Seven days after sympathectomy the content of RNA increases, reaching control levels. Beginning from the 20th day it decreases and remains at a low level for 90 days. This decrease is observed on both sides of the brain. The content of nuclear DNA is significantly reduced seven days following removal of superior cervical ganglion. The possible mechanisms of the alterations observed are discussed in connection with changes in correlation of nucleic acids with nuclear proteins.
ISSN:0507-2972