Complement and immunoglobulin levels in pregnant women with EPH gestosis

• Published in: Srpski arhiv za celokupno lekarstvo Vol. 117; no. 7-8; p. 459
• Main Authors: Rosić, B, Sulović, V, Juznić, N, Lazarević, B, Vidanović, M
• Format: Journal Article
• Language: Serbian
• Published: Serbia 01-07-1989
• Subjects: Complement Factor B - analysis; Complement System Proteins - analysis; Female; Humans; Immunoglobulins - analysis; Pre-Eclampsia - immunology; Pregnancy
• ISSN: 0370-8179

The authors determined C3 and C4 complements, factor B properdin and immunoglobulins G, M and A in 20 healthy pregnant patients and in 20 patients with EPH gestosis. The analysis was performed in mothers sera, umbilical sera and amniotic fluid, and properdin factor B and IgG in urine. They used the nonfellometric technique with immunochemistry analyzer. The C3 complement was very increased in the serum of mothers with EPH gestosis, and complement C4 was slightly increased in the serum of EPH gestosis, and complement C4 was slightly in the serum of EPH gestosis, and complement C4 was slightly increased in the serum of mothers and umbilical sera. Factor B properdin was very increased in mothers sera and decreased in urine. Higher concentrations of immunoglobulin G were found in umbilical sera than in mothers sera. Increased concentrations of sera in mothers, the umbilicus and urine were observed in patients with EPH gestosis. In these patients IgM was decreased in the serum of mothers and the umbilicus. IgM was decreased in the serum of mothers and significantly increased in umbilical sera. Significant changes in patients with EPH gestosis were noted.