Clinical evaluation of new antidepressive agents

The second generation of antidepressants have been developed with the goal to reduce cardio-toxic effects and to further a more specific action on neurotransmitter systems. However some standardized actual parameters, clinical, biological and pharmacological may be accepted as reasonable elements in...

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Bibliographic Details
Published in:	Encéphale Vol. 17 Spec No 1; p. 133
Main Authors:	Ballus, C, Gasto, C
Format:	Journal Article
Language:	French
Published:	France 01-05-1991
Subjects:	Antidepressive Agents - therapeutic use Clinical Trials as Topic Depressive Disorder - diagnosis Depressive Disorder - drug therapy Diagnosis, Differential Humans
Online Access:	Get more information
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Summary:	The second generation of antidepressants have been developed with the goal to reduce cardio-toxic effects and to further a more specific action on neurotransmitter systems. However some standardized actual parameters, clinical, biological and pharmacological may be accepted as reasonable elements in evaluating the therapeutic effects. Among them we will distinguish the diagnostic instruments which define categories of affective disorders; rating scales to assess gravity, the type of clinical test, duration of the test and finally those biological variables which should be an integral part of the evaluation of new antidepressants.
ISSN:	0013-7006