Levels of insulin, C-peptide and glucagon in the neonatal period

• Published in: Anales españoles de pediatría Vol. 19; no. 3; p. 170
• Main Authors: Pedraz García, C, Pedraz García, M J, Benito Zaballos, F, Carbajosa Herrero, T, García González, P, Soler Ripoll, J J, Salazar Villalobos, V
• Format: Journal Article
• Language: Spanish
• Published: Spain 01-09-1983
• Subjects: C-Peptide - blood; Female; Fetal Blood - analysis; Fetal Distress - blood; Glucagon - blood; Glucose - administration & dosage; Humans; Infant, Newborn; Insulin - blood; Labor, Obstetric; Maternal-Fetal Exchange; Pregnancy
• ISSN: 0302-4342

Umbilical cord plasmatic levels of insulin, peptido-C and glucagon in two groups of normal and stressed newborns, in the first and third days of life and were measured and compared with those of their mothers. The levels of insulin were significantly higher in normal newborns (p less than 0.001) than in their mothers but not significant with those found in the stressed newborn. After three days of life the mean values on insuline were 14.67 +/- 7.2, without significant differences with the other two groups. The mean values of peptido-C were not significantly different in the three groups. The molar relation in every case was higher than 1. The levels of glucagon in umbilical cord of normal newborn were 196.42 +/- 51.45 with significant elevation (p less than 0.05) after three days of life. In stressed newborn group the values in umbilical cord were significantly higher (p less than 0.01) than the foud values in normal newborn.