Differences in serotonin receptor types I and II binding in the brain regions of rats with 2 types of hereditary arterial hypertension

Serotonin C1- and C2-receptor binding was studied in various segments of the brain in two strains of rats with hereditary arterial hypertension--spontaneously hypertensive (SHR) and hereditary stress-induced hypertensive rats (HSIHR). In the hypothalamus, there was a higher C1-receptor binding in HS...

Full description

Saved in:

Bibliographic Details
Published in:	Kardiologiia Vol. 30; no. 3; p. 87
Main Authors:	Piianzin, A I, Avgustinovich, D F, Popova, N K, Markel', A L
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-03-1990
Subjects:	Animals Binding Sites Brain - metabolism Hypertension - etiology Hypertension - genetics Hypertension - metabolism Hypertension - psychology Male Rats Rats, Inbred SHR Rats, Inbred Strains Receptors, Serotonin - metabolism Serotonin - metabolism Stress, Psychological - complications
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Serotonin C1- and C2-receptor binding was studied in various segments of the brain in two strains of rats with hereditary arterial hypertension--spontaneously hypertensive (SHR) and hereditary stress-induced hypertensive rats (HSIHR). In the hypothalamus, there was a higher C1-receptor binding in HSIHR than in Wistar rats. SHR showed a higher C2-receptor binding in the cortex and C1-receptor one in the pons than did HSIHR. The changes found are suggestive of both similarities and differences in the serotonin receptor system in the two strains of rats with hereditary arterial hypertension.
ISSN:	0022-9040