Ultrastructural characteristics of experimental tumors of the intestine
Tumors of the rat large intestine induced by subcutaneous injection of 1,2-dimethylhydrazine were studied by the method of electron microscopy. Adenocarcinomas retained histiotypical differentiation and at the same time consisted mostly of cells with a low rate of differentiation. Just on the contra...
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| Published in: | Voprosy onkologij Vol. 22; no. 1; p. 59 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | Russian |
| Published: |
Russia (Federation)
1976
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| Abstract | Tumors of the rat large intestine induced by subcutaneous injection of 1,2-dimethylhydrazine were studied by the method of electron microscopy. Adenocarcinomas retained histiotypical differentiation and at the same time consisted mostly of cells with a low rate of differentiation. Just on the contrary, in mucous and signet-ring cell carcinomas the picture of an advanced cell differentiation was observed in a complete loss of organogeny. The greatest malignancy of neoplasms (signet-ring carcinoma), which cells are characterized by a high degree of cytological differentiation, is a manifestation of independence of tumor progression signs. |
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| AbstractList | Tumors of the rat large intestine induced by subcutaneous injection of 1,2-dimethylhydrazine were studied by the method of electron microscopy. Adenocarcinomas retained histiotypical differentiation and at the same time consisted mostly of cells with a low rate of differentiation. Just on the contrary, in mucous and signet-ring cell carcinomas the picture of an advanced cell differentiation was observed in a complete loss of organogeny. The greatest malignancy of neoplasms (signet-ring carcinoma), which cells are characterized by a high degree of cytological differentiation, is a manifestation of independence of tumor progression signs. |
| Author | Pozharisskiĭ, K M Savost'ianov, G A |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/178104$$D View this record in MEDLINE/PubMed |
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| Snippet | Tumors of the rat large intestine induced by subcutaneous injection of 1,2-dimethylhydrazine were studied by the method of electron microscopy. Adenocarcinomas... |
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| StartPage | 59 |
| SubjectTerms | Adenocarcinoma - pathology Adenocarcinoma, Mucinous - pathology Animals Cell Differentiation Intestinal Neoplasms - pathology Intestine, Large - ultrastructure Male Neoplasms, Experimental - pathology Rats |
| Title | Ultrastructural characteristics of experimental tumors of the intestine |
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